About the Silverman Lab
The goal of the Silverman Lab is to understand the basic mechanisms of intracellular transport to help inform the cellular etiology of “transportopathies.” Led by Michael Silverman, PhD, his group studies the process of microtubule-based transport by imaging fluoresently-labeled cargos and motor proteins in living neurons. Recently, the Silverman lab has investigated the implications of phosphorylation on KIF1A transport and are looking to uncover knowledge that drives future treatment options for mutations in transportation proteins. Furthermore, Dr. Silverman co-authored research literature highlighting therapeutic challenges and ideas for curing KIF1A/KIF1C related Hereditary Spastic Paraplegia by advancing our understanding of the disease mechanism.
