About the Vallee Lab
Richard Vallee, PhD, has a long-standing research interest in biological phenomena involving motor proteins. Historically, Dr. Vallee has had a major emphasis on cytoplasmic dynein, describing its role in many cellular processes. More recently, Dr. Vallee and team have begun to investigate the role of KIF1A in brain development, specifically during basal nuclear migration and in BDNF transport and secretion, which, in turn, markedly affects neuronal migration. In addition to these in vivo results the Vallee lab has now partnered with the labs of Dr. Wendy Chung at Columbia and Dr. Arne Gennerich at Albert Einstein College of Medicine to systematically study human disease-causing KIF1A mutations at the genotypic, phenotypic, and single-molecule level.
